Conference and Journal Citations
TEDx Talk on the Epigenetic Origins of Chronic Disease
“When will we decide to conquer chronic disease? The moment we realize the future’s not only in our genes but also in our hands with the choices we make regarding food and nutrition. We now know how we grow before we are born, matters. A woman who is pregnant with a daughter is nourishing the egg that may someday become her grandchild. We must remove the vulnerability for developing chronic disease before it starts. Through the right choices in Family, School, Workplace & Policy – we can position humanity towards a sustainable, more livable answer. Dr. Kent L. Thornburg received his PhD in Developmental Physiology and studied Cardiovascular Physiology as a National Institutes of Health (NIH) Postdoctoral Fellow at Oregon Health & Science University (OHSU). He participates in co-funded projects with scientists in England, New Zealand, France, Finland and Australia. He serves regularly on advisory panels at the NIH, the American Heart Association and the Children’s Heart Foundation and recently served as Co-Chair of the task force to determine the 10-year vision of the developmental origins of health and disease for the National Institute of Child Health and Human Development.”
This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at http://ted.com/tedx.
Peer-Reviewed Article on Unified Protocols for Cardiometabolic Care at BCBS Louisiana
Am J Manag Care. 2017 Dec 1;23(12):e402-e408.
PMID: 29261245 Free Article
The program was associated with a shift in primary care delivery and reductions in overall cost.
Savings versus the control group were $27.09 per member per month (PMPM). (P ≤.001).
Cost savings were derived largely from a decrease in hospitalizations—a difference of $18.85 PMPM (P = .0023).
Additional savings were associated with shifts in healthcare utilization by the intervention group toward proactive management, including increased primary care visits (P = .0106) and screening for diabetes (P = .0019).
Inpatient admissions also decreased, most significantly among those with chronic conditions (P <.05).
Peer-Reviewed Articles on a Unified Hypothesis of Cardiometabolic Diseases (CMDs) and Related Topics
Cardiorenal Med. 2011;1(4):211-219. Epub 2011 Oct 4.
PMID: 22135630 Free PMC Article
Excess saturated fats and glucose may initiate methylation of arginine residues in proteins involved in transcription of genes mediating inflammation, cell proliferation, apoptosis, and oncogenesis.
Gentry CK, Cross LB, Gross BN, McFarland MS, Bestermann WH.
South Med J. 2011 Jan;104(1):24-8. doi: 10.1097/SMJ.0b013e3181fa7230.
Bestermann WH Jr.
J Fam Pract. 2010 May;59(5 Suppl):S3-8. No abstract available.
Neutel JM, Bestermann WH, Dyess EM, Graff A, Kursun A, Sutradhar S, Yunis C.
J Clin Hypertens (Greenwich). 2009 Jan;11(1):22-30. doi: 10.1111/j.1751-7176.2008.00058.x.
PMID: 19125855 Free Article
Bestermann WH Jr.
MedGenMed. 2007 Dec 10;9(4):54. No abstract available.
PMID: 18311403 Free PMC Article
Calvert JW, Gundewar S, Jha S, Greer JJ, Bestermann WH, Tian R, Lefer DJ.
Diabetes. 2008 Mar;57(3):696-705. Epub 2007 Dec 14.
PMID: 18083782 Free Article
Houston MC, Basile J, Bestermann WH, Egan B, Lackland D, Hawkins RG, Moore MA, Reed J, Rogers P, Wise D, Ferrario CM.
Am J Med Sci. 2005 Jun;329(6):276-91. Review.
Bestermann WH, Lackland DT, Riehle JE, Egan BM.
South Med J. 2004 Oct;97(10):932-8.